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Fecal Transplant

Fecal Transplant: Early History of FMT

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4.85
60,385 ratings · 28,670 reviews
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Fecal Transplant

Fecal Transplant: Early History of FMT

4.85 60,385 ratings · 28,670 reviews
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Overview: Infection with antibiotic-resistant microbes, often referred as "super-bugs," in hospitals can be a common problem. A conventional solution to the problem is to find a new antibiotic. This solution simply accelerates an arms race between microbes and pharmaceutical companies which try to develop an effective antibiotic. We should search for a completely new approach to the problem. This book might suggest an alternative approach for the superbug problem.It describes the tragic experience of a student nurse, Betty, who performed the world's first fecal transplant. It is not well known to the general public, but there are some diseases that infect mostly patients in hospitals. These diseases are often referred to as post-operative complications or a new infection, due to patients' weakened immune system. Pseudo membranous colitis (PM colitis) was one of such diseases, which predominantly affects patients after surgery of the digestive system. It had a high fatality rate, but there was no known effective treatment. An odd circumstance pushed Betty to perform the world's first fecal transplant and demonstrate its effectiveness. However, because of the stigma attached to feces, fellow medical staff ridiculed her to such a degree that she could not remain as a staff nurse. Later academic researchers identified the pathogen of PM colitis as Clostridium difficile (C. diff), and renamed the disease C-diff infection. Again although fecal transplant was an effective treatment for the disease, the mainstream establishment of the medical community ignored the treatment. When C. diff evolved an antibiotic-resistant strain, hundred-thousands of patients died in hospitals every year around the world. In the United States, bureaucratic hurdles prevented research of fecal transplant, despite such a high mortality rate. Eventually, the effectiveness of fecal transplant spread on the Internet and many patients started doing by themselves with help of friends and relatives because medical doctors were unwilling to perform such illegal treatment. In 2013, after more than fifty years from Betty's action, FDA finally and reluctantly allowed doctors to perform fecal transplant for limited cases of C-diff infection. Meanwhile Betty suffered personal tragedy, but she finally retired and enjoyed her peaceful life knowing that the mainstream of the medical community accepted fecal transplant, even for limited cases. This book also comments on the FDA and NIH's role in new drug development, especially concerned about Ebola epidemic.

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Topics & Genres

Pages 63
Language Eng
Publisher Indian Town Press
Published May 13, 2015
ISBN 26835810
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Yashi Nozawa
About the Author
Yashi Nozawa
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Yashi Nozawa writes contemporary fiction and has always been fascinated by character-driven stories. They hold a degree in English Literature and previously worked as an editor before transitioning to writing their own books. Yashi Nozawa lives with their spouse and a very vocal rescue cat.

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Sarah Ramirez
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Such a rich narrative. The prose is exquisite. It’s accessible yet undeniably sophisticated. Worth every moment spent reading.
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I thoroughly enjoyed the elegance of it. A brilliant concept executed with flair. Just a few pacing choices I would change. A wonderful companion for a quiet weekend.
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Such a rich narrative. The prose is exquisite. It’s accessible yet undeniably sophisticated. I am now a lifelong fan of this author.
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Honestly one of the most premium reading experiences lately. The author orchestrated a breathtaking finale. Truly a work of art. I will undoubtedly revisit this masterpiece.
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I was completely blown away. The prose is exquisite. It’s accessible yet undeniably sophisticated. A true literary gem.
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Masterpiece from start to finish. I became deeply invested in the protagonist's journey. A masterclass in storytelling. A true literary gem.
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I was completely blown away. I adored how the story unfolded. It kept me captivated without sacrificing elegance. I will undoubtedly revisit this masterpiece.
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Patricia Sanchez July 05, 2025
A profoundly satisfying read. The prose is exquisite. It’s accessible yet undeniably sophisticated. A true literary gem.
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Sharon Moore
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Masterpiece from start to finish. The author orchestrated a breathtaking finale. Truly a work of art. An effortless 5 stars.
Jacob Clark
Jacob Clark December 22, 2025
It was adequate. It possessed moments of brilliance, but the narrative felt slightly disjointed ultimately. Unlikely to reread, but a reasonable expenditure of time.
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Joshua Evans December 31, 2024
Such a rich narrative. The pacing was impeccable and the characters felt incredibly authentic. I was completely immersed. A true literary gem.
Melissa Martinez
Melissa Martinez March 21, 2025
I was completely blown away. The author orchestrated a breathtaking finale. Truly a work of art. Worth every moment spent reading.
Robert Hill
Robert Hill July 07, 2025
Exceeded all my expectations. The author orchestrated a breathtaking finale. Truly a work of art. I am now a lifelong fan of this author.
Laura Roberts
Laura Roberts August 31, 2025
Exceeded all my expectations. The prose is exquisite. It’s accessible yet undeniably sophisticated. I will undoubtedly revisit this masterpiece.
James Sanchez
James Sanchez April 29, 2024
I was completely blown away. The prose is exquisite. It’s accessible yet undeniably sophisticated. Worth every moment spent reading.
Christopher Rodriguez
Christopher Rodriguez June 29, 2025
A highly sophisticated read. The middle had a deliberate pace, but the climax was phenomenal. I would highly recommend this to discerning readers.
Lisa Hill
Lisa Hill May 01, 2025
A profoundly satisfying read. The prose is exquisite. It’s accessible yet undeniably sophisticated. An effortless 5 stars.
Brian Campbell
Brian Campbell November 02, 2025
I was completely blown away. The pacing was impeccable and the characters felt incredibly authentic. I was completely immersed. A true literary gem.
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A profoundly satisfying read. It strikes a perfect harmony of dialogue and world-building. Every chapter felt necessary. I am now a lifelong fan of this author.
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Took a moment to build, but the payoff was spectacular. Beautiful writing, though I craved slightly more depth in the lore. Still, undeniably engaging. A wonderful companion for a quiet weekend.
Patricia Garcia
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Robert Gomez
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Exceeded all my expectations. I adored how the story unfolded. It kept me captivated without sacrificing elegance. An effortless 5 stars.
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A very strong entry. The protagonist was compelling, though some subplots felt slightly overshadowed. Quite impressive overall.
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I was completely blown away. I adored how the story unfolded. It kept me captivated without sacrificing elegance. An absolute must-read for connoisseurs of the genre.
Sarah Ramirez
Sarah Ramirez April 03, 2024
Excellent, though slightly flawed. Beautiful writing, though I craved slightly more depth in the lore. Still, undeniably engaging. Quite impressive overall.
Paul Lopez
Paul Lopez March 13, 2025
Such a rich narrative. I adored how the story unfolded. It kept me captivated without sacrificing elegance. I will undoubtedly revisit this masterpiece.
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