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Current Topics in Microbiology and Immunology, Volume 353: Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing

Penned By Charles E. Samuel
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Current Topics in Microbiology and Immunology, Volume 353: Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing

Penned By Charles E. Samuel
4.85 41,237 Ratings
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Editor's Note:
The objective of this" CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins.

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Released September 28, 2011
Identifier (ISBN) 12081171
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Charles E. Samuel
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Charles E. Samuel

After spending years working in the corporate world, Charles E. Samuel finally decided to pursue a lifelong passion for writing. They currently reside in a quiet suburb where they spend most of their time outlining new stories, reading extensively, and occasionally attempting to bake.

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George Wilson
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"I was completely blown away. The prose is exquisite. It’s accessible yet undeniably sophisticated. I will undoubtedly revisit this masterpiece."
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Ashley Perez
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